Introduction: the rise of peptides in cosmetics
For several years now, peptides have occupied a central place in advanced skincare formulas. These small chains of amino acids, natural fragments of proteins, play a key role in cellular communication. In cosmetics, they are used to stimulate essential biological mechanisms: production of collagen and elastin, skin regeneration, improved firmness, and strengthening the skin barrier.
Among the many peptides available, hexapeptide-11 attracts attention due to its natural origin and multifunctional effects on the skin. 
What is Hexapeptide-11?
Hexapeptide-11 is a biomimetic peptide composed of six amino acids. It was originally isolated from brewer's yeast (Saccharomyces cerevisiae) cultures , a rich natural source of peptides and growth factors.
Unlike other purely technological synthetic peptides, it therefore benefits from a natural fermentation origin while being reproduced in a controlled manner for consistent quality.
Mechanisms of action
Scientific research suggests several mechanisms by which hexapeptide-11 acts at the cutaneous level:
- Stimulation of genes linked to the synthesis of collagen and elastin : it helps to improve the firmness and elasticity of the skin.
- Regulation of metalloproteinases (MMPs) : These enzymes are responsible for the breakdown of support fibers; hexapeptide-11 helps limit their activity.
- Hormonal biomimetic effect : some studies indicate that it can partially mimic the action of DHEA (dehydroepiandrosterone), a hormone associated with cellular vitality, the levels of which decrease with age.
- Improved cell regeneration : It promotes the renewal of the extracellular matrix and helps maintain youthful-looking skin.
Scientific results
In vitro and ex vivo tests have highlighted several benefits:
- Increase in collagen and elastin expression up to +30% after 7 days of application.
- Visible improvement in skin firmness after 4 weeks of topical use in skincare formulas.
- Reduction in roughness and the appearance of fine wrinkles thanks to better organization of dermal fibers.
These results position hexapeptide-11 as a global anti-aging active ingredient, targeting both the prevention and correction of the signs of aging .
Cosmetic applications
Hexapeptide-11 is found in several types of high-end skincare products:
- Anti-aging serums to smooth and firm skin
- Day or night creams aimed at restoring elasticity and tone
- Eye contour care to improve firmness and radiance
- Anti-sagging formulas specific to the neck and décolleté
Its “pro-collagen and pro-elastin” profile makes it an ideal active ingredient for overall firmness and skin revitalization treatments.
Conclusion
Hexapeptide-11 is a cutting-edge peptide that combines biotechnological innovation with natural inspiration. Thanks to its stimulating properties on collagen and elastin, it helps maintain firmer, more elastic and visibly rejuvenated skin. Find it in our "botox-like" effect Peptide Lift Serum.
Integrated into a cosmetic routine, it represents an effective and respectful alternative to invasive approaches, while offering a valuable ally in the fight against skin aging.
At Innadermys we have integrated it into our Peptide Lift Serum.
