Premature skin aging and inflammation

When the skin functions under stress

Skin aging isn't solely determined by the passage of time. Certain lifestyle factors, environmental factors, and skincare routines can influence how skin changes over the years. When these factors accumulate, skin can lose comfort, radiance, and evenness more quickly.
Among the mechanisms often mentioned in this context: low-grade skin inflammation , a natural response of the skin which, when stressed too frequently, can disrupt its overall balance.

At Innadermys, we consider the skin as a living system to be supported , not as a problem to be corrected.

Inflamed skin: a fragile balance

Skin inflammation is, in origin, a normal physiological mechanism . It allows the skin to react to external aggressions such as UV rays, pollution, friction or certain unsuitable formulas.
When these stresses are repeated, the skin can remain in a state of permanent response. This state of imbalance contributes to skin that is more reactive, less comfortable, and more uneven over time.

This persistent inflammation triggers a cascade of biological reactions that directly affect its structure.

Collagen and elastin: accelerated degradation

Chronic inflammation stimulates the production of enzymes (notably metalloproteinases) that participate in the degradation of collagen and elastin .

Result :

  • a noticeable loss of firmness
  • less toned skin
  • the more pronounced appearance of signs of aging

👉 The skin gradually loses its ability to maintain and repair itself .

Weakened skin barrier: more vulnerable skin

Prolonged inflammation also damages the skin barrier , which is essential for protection and hydration.

Consequences :

  • increased water loss
  • skin is more reactive, more sensitive
  • facilitated penetration of irritants and pollutants

👉 The more the barrier is weakened, the more the inflammation perpetuates itself.

Oxidative stress: when the skin is exhausted

External aggressions and inflammation promote the excessive production of free radicals .
This phenomenon, called oxidative stress , accelerates cellular aging.

Visible signs:

  • dull complexion and loss of radiance
  • irregular texture
  • skin that looks “tired”

👉 The skin devotes its energy to defending itself, at the expense of its renewal.

Slowed cell renewal and altered skin texture

Skin under chronic inflammation renews its cells more slowly .

This translates to:

  • accumulation of dead cells
  • uneven skin texture
  • pores more visible
  • loss of brightness

👉 Premature aging is not just about wrinkles, but about overall skin quality .

Slowing down aging: a respectful and functional approach

Slowing down aging does not mean fighting against the skin, but reducing the factors that disrupt its natural functioning .

Respect the skin

Avoiding over-stimulation, overly aggressive active ingredients and excessive routines allows the skin to maintain its ability to adapt.

Protecting on a daily basis

Protection against external aggressions and support of the skin barrier help to preserve skin quality over time.

Acting also from within

Lifestyle, diet, sleep, and stress management directly influence the appearance and comfort of the skin.

Use the right assets at the right time

At Innadermys, a rich formula does not mean overload.
Each active ingredient is selected for its compatibility with skin biology and for its precise role within the formulation.

Rather than focusing on a single, highly stimulating ingredient, we favor a synergy of complementary active ingredients —hydrating, soothing, protective, and antioxidant—integrated into carefully controlled formulations and used at gentle concentrations. This approach supports the skin's natural functions on multiple levels, without disrupting its balance or causing irritation.

Hydration, strengthening the skin barrier, preserving radiance, and improving comfort are not isolated actions, but closely linked mechanisms. By addressing them together, the skin is less stressed and functions more smoothly and stably over time.

👉 The challenge is not to do more, but to formulate accurately , respecting the biological rhythm of the skin.

Regulating renewal without shocking the skin

Retinol is widely recognized for its ability to improve skin appearance and support skin renewal. However, its highly stimulating nature may not be suitable for all skin types, particularly those that are sensitive, reactive, or already weakened by inflammation.

In these situations, some plant-based alternatives, such as phytoretinol derived from Bidens pilosa , offer a more gradual approach.
This type of active ingredient is appreciated for its good tolerance and its ability to support skin renewal without causing marked irritation , making it an interesting option for sensitive or uncomfortable skin, often better accepted than other plant-based alternatives such as bakuchiol.

👉 The goal is not to accelerate the skin, but to respect its biological rhythm .

Antioxidants: preserving balance against aggressions

Daily exposure to UV rays, pollution, and stress promotes oxidative stress , a natural phenomenon that can influence how the skin's appearance changes over time.

Antioxidants help the skin cope with these environmental aggressors by supporting its natural protective mechanisms. Incorporated into balanced formulations, they contribute to:

  • preserve the radiance and evenness of the complexion
  • limit the impact of external aggressions on the skin
  • to support skin resilience

Among the antioxidants commonly used in cosmetics, we find in particular certain forms of vitamins (such as vitamin C or E) , polyphenols of plant origin , or even botanical extracts recognized for their ability to support the skin in the face of environmental stress.

👉 Better protected skin is skin that more easily retains its quality over time.

Hydrate, soothe and strengthen the skin barrier

In the context of fragile or uncomfortable skin, hydration is not limited to the supply of water.
It also plays a key role in maintaining the skin barrier , which is essential for skin balance and comfort.

Certain assets are particularly recognized for supporting this function:

  • Ceramides , naturally present in the skin, help maintain the skin barrier.
  • Bisabolol , valued for its soothing properties
  • Aloe vera , known to contribute to skin hydration and comfort

Prebiotics and postbiotics , used to support the balance of the skin's ecosystem, can be added to these active ingredients. By promoting a more harmonious environment on the skin's surface, they contribute to maintaining its stability and daily comfort.

When properly integrated, these active ingredients contribute to skin that is more comfortable, more stable and better prepared to face external aggressions.

Conclusion

Premature skin aging is rarely linked to a single factor. It most often results from a combination of imbalances that gradually influence its function and appearance.

By adopting a respectful, protective and consistent approach, it is possible to sustainably preserve the quality of the skin and its natural balance.

Because skin that ages better is first and foremost skin that is cared for intelligently .

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